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Talk with your physician before altering any protocol or supplement/pharmaceutical.
Many times one is not yet ready to take methylfolate.
PART 1The biggest differences in recommendations between these two types of mutations are: Typical Pharmaceuticals Recommended for the C677T MTHFR Mutation There are many pharmaceuticals commonly recommended for C677T MTHFR mutations yet they are ill-advised as they contain inferior forms of vitamin B12, little or no vitamin B6 or the incorrect form of folic acid.
It should also be known that all pharmaceutical drugs below contain food coloring, dyes, anti-caking agents or other compounds that should be avoided.
Have one or two copies of the MTHFR C677T mutation? After working with 1000’s of individuals with this defect, I’ve developed a protocol which may help a significant number of people.
UPDATE 3/16/2015: Having written this article years ago now, I must let you know that if ANYONE – with or without MTHFR C677T or A1298C snps/variants/polymorphisms/mutations – whatever you want to to call them – should follow the lifestyle, dietary and environmental recommendations.
This is not harmful and will subside in about 20 to 30 minutes. It is methylation that is severely disrupted in those with C677T MTHFR mutations – especially homozygous individuals. If methylation becomes excessive, side effects will occur as noted above. There is a need for routine adjustment as our bodies are dynamic.
PART IIMethylfolate Recommendations for those homozygous for the C677T MTHFR Mutation: Once you have determined you respond well to the probiotics, krill oil, turmeric and vitamin E, then you may proceed to slowly adding the following.NOTE: If you are sensitive to supplements in general, then it is recommended to start with a comprehensive multivitamin and multimineral as this supports numerous biochemical functions within your body.It also provides a fast testing ground to see if you respond well to numerous nutrients.Consider taking 100 mg or 1/5th tablet of Niacin if these symptoms occur.It is a good idea to have a bottle of Niacin on hand in case these symptoms occur from taking too much methylfolate.